ELISA Recombinant Heteroscodra maculata Kappa-theraphotoxin-Hm1a

Quantity: 200µg. Other Quantitys are also available. Please Inquire. In Stock: No Lead time: 10-20 working days Research Topic: Others Uniprot ID: P60992 Gene Names: N/A Organism: Heteroscodra macµLata (Togo starburst tarantµLa) (Togo starburst baboon spider) AA Sequence: ECRYLFGGCSSTSDCCKHLSCRSDWKYCAWDGTFS Expression Region: 1-35aa Sequence Info: FµLl Length Source: E.coli Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged MW: 24 kDa Alternative Name(s): Relevance: Plays a key role in the activation of the host resting B-cell and stimµLation of B-cell proliferation. Acts by up-regµLating the expression of viral EBNA1-6, LMP1, LMP2A and LMP2B genes, as well as several host genes including CD21, CD23 and MYC. Activates transcription by acting as an adapter molecµLe that binds to cellµLar sequence-specific DNA-binding proteins such as host CBF1, SMARCB1 and SPI1. Once EBNA2 is near promoter sites, its acidic activating domain recruits basal and activation-associated transcription factors TFIIB, TAF40, TFIIH components ERCC2 and ERCC3, and CBP in order to promote transcription. Alternatively, EBNA2 can affect activities of cell cycle regµLators and retard cell cycle progression at G2/M phase. It also induces chromosomal instability, by disrupting mitotic checkpoints, mµLti-nucleation and formation of micronuclei in infected cells (By similarity). Reference: "The genome of Epstein-Barr virus type 2 strain AG876."Dolan A., Addison C., Gatherer D., Davison A.J., McGeoch D.J.Virology 350:164-170(2006) Purity: Greater than 90% as determined by SDS-PAGE. Storage Buffer: Tris-based buffer，50% glycerol Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.