ELISA MIEF1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:MIEF1 antibody; MID51 antibody; SMCR7L antibody; Mitochondrial dynamics protein MID51 antibody; Mitochondrial dynamics protein of 51 kDa antibody; Mitochondrial elongation factor 1 antibody; Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like antibody; SMCR7-like protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NQG6 Immunogen:Recombinant Mitochondrial dynamics protein MID51 protein (51-309AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Mitochondrial outer membrane protein which regµLates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. RegµLates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, althoµgh with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimµLate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubµLes with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MIEF1 Research Areas:Cell biology