ELISA MKRN1 anti-

Quantity :50µg Clone Number: Aliases:E3 ubiquitin-protein ligase makorin-1 antibody; FLJ21334 antibody; HGNC:7112 antibody; Makorin antibody; Makorin ring finger protein 1 antibody; MKRN 1 antibody; mkrn1 antibody; MKRN1_ antibody; OTTHUMP00000212117 antibody; OTTHUMP00000212118 antibody; OTTHUMP00000212121 antibody; OTTHUMP00000212124 antibody; Ring finger protein 1 antibody; RING finger protein 61 antibody; RNF61 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UHC7 Immunogen:Recombinant E3 ubiquitin-protein ligase makorin-1 protein (109-209AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:500-1:1000 Background:E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimµLates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regµLator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MKRN1 Research Areas:Epigenetics and Nuclear Signaling; Cell biology